The metabolic role of PFKFB4 in androgen-independent growth in vitro and PFKFB4 expression in human prostate cancer tissue

Table 1 Comparison of the expression of PFKFB4 among different types of PCa tissue and BPH tissue

Group		PFKFB4 expression		Number (n)	Total (n)	P-value^*
Group		Negative (n)	Positive (n)	Number (n)	Total (n)	P-value^*
PCa^a and BPH	PCa^a	7	18	25	40	0.000
PCa^a and BPH	BPH	15	0	15	40	0.000
PCa^b and adjacent tissue	PCa^b	11	14	25	50	0.001
PCa^b and adjacent tissue	Adjacent tissue	23	2	25	50	0.001
Before and after therapy^c	Before therapy^d	11	14	25	50	0.377
Before and after therapy^c	After therapy^e	7	18	25	50	0.377

^{a, e}Radical prostatectomy tissue samples; ^{b, d}preoperative biopsy tissue; ^cbiopsy tissue collected before hormonal therapy and surgical tissue collected after hormonal therapy, with both samples derived from the same patient. ^*Based on the Fisher’s exact test

ISSN: 1471-2490