Table 2 Comparison of clinical and surgical data between younger (< 65 years) and elderly patients (≥ 65 years) with small renal masses
< 65 years (n = 949) | ≥ 65 years (n = 574) | p Value * | |
|---|---|---|---|
Gender | |||
Male n (%) | 644 (68.1) | 378 (66.3) | 0.496 |
Female n (%) | 301 (31.9) | 192 (33.7) | |
Comorbidities n (%) | |||
Yes | 552 (61.3) | 387 (72.6) | < 0.001 |
No | 349 (38.7) | 146 (27.4) | |
Hypertension n (%) | 115 (18.0) | 128 (37.8) | < 0.001 |
Obesity n (%) | |||
Yes | 229 (24.9) | 131 (23.6) | 0.634 |
No | 691 (75.1) | 423 (76.4) | |
Smoking n (%) | |||
Yes | 339 (35.7) | 190 (33.1) | 0.324 |
No | 610 (64.3) | 384 (66.9) | |
Symptomatic at presentation n (%) | |||
Yes | 442 (46.6) | 260 (45.3) | 0.666 |
No | 507 (53.4) | 314 (54.7) | |
Serum Creatinine - mg/dL | |||
Baseline - Mean (SD) | 1.04 (0.81) | 1.17 (0.92) | 0.045 |
Median (Q1 – Q3) | 0.96 (0.83–1.1) | 1.0 (0.83–1.2) | |
Post-operative - Mean (SD) | 1.20 (0.79) | 1.35 (1.22) | 0.143 |
Median (Q1 – Q3) | 1.1 (0.9–1.33) | 1.2 (1.01–1.41) | |
Tumor size | |||
≤ 3 cm n (%) | 487 (62.3) | 255 (55.6) | 0.023 |
> 3 cm n (%) | 295 (37.7) | 204 (44.4) | |
Surgical treatment | |||
Partial Nephrectomy n (%) | 602 (69.7) | 295 (59.7) | < 0.001 |
Radical Nephrectomy n (%) | 262 (30.3) | 199 (40.3) | |
Histologic subtype | |||
Clear cell n (%) | 401 (64.8) | 250 (64.3) | 0.921 |
Non-clear cell n (%) | 218 (35.2) | 139 (35.7) | |
Nuclear grade n (%) | |||
Low grade | 224 (23.6) | 166 (28.9) | 0.025 |
High grade | 725 (76.4) | 408 (71.1) | |
Extracapsular extension n (%) | |||
Yes | 81 (10.9) | 60 (14.0) | 0.140 |
No | 661 (89.1) | 368 (86.0) | |
ECOG | |||
0–1 n (%) | 912 (96.1) | 543 (94.6) | 0.212 |
≥ 2 n (%) | 37 (3.9) | 31 (5.4) | |
Karnofsky | |||
≤ 80 n (%) | 73 (7.7) | 69 (12.0) | 0.006 |
> 80 n (%) | 876 (92.3) | 505 (88.0) | |
ASA classification | |||
1–2 n (%) | 822 (86.6) | 421 (73.3) | < 0.001 |
≥ 3 n (%) | 127 (13.4) | 153 (26.7) | |