Contrast-enhanced transrectal ultrasound can reduce collection of unnecessary biopsies when diagnosing prostate cancer and is predictive of biochemical recurrence following a radical prostatectomy in patients with localized prostate cancer

Table 1 Efficacy of CETRUS with a cut-off score of 2 in reducing unnecessary prostate biopsies

Biopsy strategy	No. of biopsies	No. of necessary biopsies^a	No. of unnecessary biopsies^a
Conventional standard	347	164	183
Combining CETRUS score ≥ 2^b	305	164	141
Reduction in the no. of biopsies	42	0	42
Proportion of the reduced biopsies	12.1% (42/347)^c	0% (0/164) ^c	23.0% (42/183)

^a Necessary biopsies: performed for malignant disease as confirmed by pathologic evaluation; Unnecessary biopsies: performed for benign disease as confirmed by pathologic evaluation
^b Conventional standard of biopsy combining CETRUS blood flow scale score ≥ 2
^c Proportion of reduced biopsies without missing cancer

ISSN: 1471-2490