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Fig. 1 | BMC Urology

Fig. 1

From: Rationale, design, and methods of electroencephalography-based investigation of the effects of oral desmopressin on improving slow-wave sleep time in nocturnal polyuria patients (the DISTINCT study): protocol for a single-arm, open-label, single-assignment trial

Fig. 1

Study design. A total of 20 patients with nocturnal polyuria will participate in this study. After the conformation of eligibility, the enrolled patients will be treated with oral desmopressin 50 μg per day. In the pre-screening period, 2-day frequency volume chart (FVC) and sleep encephalography (EEG) will be recorded and the Pittsburgh Sleep Questionnaire Index (PSQI) will be completed. Before visit Day 0, 2-day FVC and EEG will be recorded. Before visit Day 7 and Day 28, 2-day FVC and EEG will be recorded. On visit Day 28, the PSQI will be completed

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