Table 1 studied clinical and pathological variables in seminoma Stage I cases. Additionally, cases are presented as aggregate and per center (Center 1 = Portuguese Institute of Oncology of Porto; Center 2 = Centro Hospitalar de Lisboa Ocidental)

N (%)

29

(50%)

(21)(8)

29

(50%)

(19)(10)

–

Median Age at Diagnosis, years (min – max)

33 (17–52)

(33)(33)

32 (21–66)

(31)(36)

0.641

Median tumor size (cm)

1.7

(1.7)(1.8)

4.5

(4.3)(4.95)

–

Min – max size (cm)

0.7–2.8

3.0–12.0

Tumor > 4 cm

-

16 (55.2%)

(9)(7)

Rete testis invasion (RTI)

2 (6.9%)

(2)(0)

12 (41.4%)

(9)(3/4^a)

< 0.0001

Median Mitosis/10 HPF

10

(10)(^a)

18

(18)(^a)

0.098

Extensive Necrosis (EN)

12 (41.4%)

(9)(3/5^a)

22 (75.9%)

(17)(5/9^a)

0.023

Anaplastic features

12 (41.4%)

(10)(2/5^a)

14 (48.3%)

(12)(2/9^a)

0.793

Adjuvant Treatment

–

 Surveillance

11 (44.0%)

6 (27.3%)

 Active treatment

14 (56.0%)

16 (72.7%)

  CT

2 (8.0%)

3 (13.6%)

  RT

12 (48.0%)

13 (59.1%)

Testicular contra-lateral metachronous tumor

1 (5.3%)

0

–

Distant Recurrence^b

2

(0)(2)

1

(0)(1)

–

Cancer-specific death

0

0

–