From: Prognostic significance of the albumin-to-globulin ratio for upper tract urothelial carcinoma
Parameter | Cutoff | Univariate | Multivariate | ||
---|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | ||
Age at surgery | Continuous | 1.03 (1.00 to 1.07) per score | < 0.05* | 1.03 (0.99 to 1.07) per score | 0.07 |
Sex | Male | Reference | 0.08 | Reference | 0.23 |
Female | 1.72 (0.93 to 3.07) | 1.48 (0.77 to 2.76) | |||
Surgical technique | Open | Reference | < 0.05* | Reference | 0.60 |
Laparoscopic | 0.44 (0.23 to 0.98) | 1.33 (0.47 to 4.03) | |||
Tumor location | Renal pelvis or both | Reference | 0.92 | Reference | 0.88 |
Ureter | 1.03 (0.58 to 1.80) | 1.05 (0.57 to 1.94) | |||
Tumor grade | G1/2 | Reference | < 0.01* | Reference | < 0.05* |
G3 | 2.61 (1.49 to 4.67) | 2.15 (1.03 to 4.52) | |||
Pathological T stage | ≤T2 | Reference | < 0.01* | Reference | 0.27 |
≥T3 | 2.30 (1.32 to 4.08) | 1.54 (0.71 to 3.35) | |||
Pathological N stage | N0/x | Reference | < 0.01* | Reference | 0.09 |
N1–3 | 4.32 (2.14 to 8.12) | 2.56 (0.87 to 7.09) | |||
Adjuvant chemotherapy | Yes | Reference | 0.33 | Reference | 0.23 |
No | 1.36 (0.73 to 2.43) | 1.62 (0.74 to 3.61) | |||
Previous or synchronous bladder cancer | No | Reference | < 0.01* | Reference | < 0.05* |
Yes | 2.43 (1.28 to 4.39) | 1.99 (1.01 to 3.75) | |||
AGR | ≥1.25 | Reference | < 0.01* | Reference | < 0.05* |
< 1.25 | 2.90 (1.66 to 5.15) | 2.09 (1.12 to 3.92) |