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Table 1 Upregulated proteins in COM-stimulated HK-2 cells (P < 0.05, FC > 2)

From: Comprehensive study of altered proteomic landscape in proximal renal tubular epithelial cells in response to calcium oxalate monohydrate crystals

Gene name

Accession

FC (C/H)

P value (C/H)

Description

LZTS1

Q9Y250

20.20

0.001

Leucine zipper putative tumor suppressor 1 OS=Homo sapiens GN = LZTS1 PE = 1 SV = 3

HES1

Q14469

16.53

0.001

Transcription factor HES-1 OS=Homo sapiens GN=HES1 PE = 1 SV = 1

NKTR

P30414

9.53

0.001

NK-tumor recognition protein OS=Homo sapiens GN=NKTR PE = 1 SV = 2

KLK15

M0R2F7

3.51

0.033

Kallikrein-15 (Fragment) OS=Homo sapiens GN=KLK15 PE = 4 SV = 1

CLPS

P04118

3.30

0.002

Colipase OS=Homo sapiens GN=CLPS PE = 1 SV = 2

DPP8

Q6V1X1

3.09

0.004

Dipeptidyl peptidase 8 OS=Homo sapiens GN = DPP8 PE = 1 SV = 1

CEP128

Q6ZU80

2.77

0.004

Centrosomal protein of 128 kDa OS=Homo sapiens GN=CEP128 PE = 1 SV = 2

PHRF1

Q9P1Y6

2.74

0.003

PHD and RING finger domain-containing protein 1 OS=Homo sapiens GN=PHRF1 PE = 1 SV = 3

HNRNPD

D6RBQ9

2.64

0.007

Heterogeneous nuclear ribonucleoprotein D0 (Fragment) OS=Homo sapiens GN=HNRNPD PE = 1 SV = 1

ANXA2

H0YL33

2.63

0.015

Annexin (Fragment) OS=Homo sapiens GN = ANXA2 PE = 1 SV = 1

TMEM141

Q96I45

2.61

0.000

Transmembrane protein 141 OS=Homo sapiens GN = TMEM141 PE = 1 SV = 1

FAU

E9PM49

2.53

0.001

40S ribosomal protein S30 (Fragment) OS=Homo sapiens GN=FAU PE = 1 SV = 8

TMSB10

P63313

2.49

0.009

Thymosin beta-10 OS=Homo sapiens GN = TMSB10 PE = 1 SV = 2

CFL1

E9PP50

2.38

0.013

Cofilin-1 (Fragment) OS=Homo sapiens GN=CFL1 PE = 1 SV = 8

RPS29

P62273

2.35

0.024

40S ribosomal protein S29 OS=Homo sapiens GN = RPS29 PE = 1 SV = 2

ACTB

C9JTX5

2.34

0.000

Actin, cytoplasmic 1 (Fragment) OS=Homo sapiens GN = ACTB PE = 1 SV = 1

ZNF12

P17014

2.32

0.001

Zinc finger protein 12 OS=Homo sapiens GN = ZNF12 PE = 1 SV = 3

GCHFR

P30047

2.27

0.013

GTP cyclohydrolase 1 feedback regulatory protein OS=Homo sapiens GN = GCHFR PE = 1 SV = 3

ZNF146

Q15072

2.23

0.000

Zinc finger protein OZF OS=Homo sapiens GN = ZNF146 PE = 1 SV = 2

TMEM222

Q9H0R3

2.17

0.002

Transmembrane protein 222 OS=Homo sapiens GN = TMEM222 PE = 1 SV = 2

ZNF574

A0A0C4DFM2

2.16

0.000

HCG1643764, isoform CRA_b OS=Homo sapiens GN = ZNF574 PE = 1 SV = 1

TSHZ1

Q6ZSZ6

2.11

0.006

Teashirt homolog 1 OS=Homo sapiens GN = TSHZ1 PE = 1 SV = 2

ITGA5

P08648

2.04

0.007

Integrin alpha-5 OS=Homo sapiens GN=ITGA5 PE = 1 SV = 2

BTF3

D6RDG3

2.02

0.004

Transcription factor BTF3 (Fragment) OS=Homo sapiens GN=BTF3 PE = 1 SV = 3