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Table 2 Univariable and multivariable logistic regression model of preoperative variables predicting pathological Gleason score ≥ 7

From: Preoperative prostate health index predicts adverse pathology and Gleason score upgrading after radical prostatectomy for prostate cancer

Variables

Univariable analysis

Multivariable analysis

OR (95% CI)

p value

Base model

OR (95% CI)

p value

Base model + PHI

OR (95% CI)

p value

Age

1.02 (0.99–1.06)

0.1462

1.02 (0.99–1.05)

0.1660

1.02 (0.99–1.06)

0.1437

DRE

1.62 (1.01–2.60)

0.0395

1.71 (1.06–2.76)

0.0261

1.63 (1.00–2.65)

0.0440

PSA

1.07 (1.02–1.12)

0.0025

1.08 (1.03–1.14)

0.0013

1.05 (0.99–1.09)

0.0531

fPSA

0.98 (0.94–1.03)

0.4477

0.92 (0.82–1.02)

0.1146

0.96 (0.89–1.04)

0.2925

p2PSA

1.01 (0.99–1.02)

0.1212

    

%p2PSA

1.03 (1.01–1.06)

0.0155

    

PHI

1.02 (1.01–1.03)

< 0.0001

  

1.02 (0197–1.03)

0.0015

  1. DRE digital rectal examination, PSA prostate specific antigen, fPSA free PSA, p2PSA [−2]proPSA, %p2PSA 2pSA/fPSA ratio, PHI Prostate Health Index, OR Odds ratio, CI confidence interval
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