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Table 3 Univariable and multivariable logistic regression model of preoperative variables predicting Gleason sum upgrading

From: Preoperative prostate health index predicts adverse pathology and Gleason score upgrading after radical prostatectomy for prostate cancer

Variables

Univariable analysis

Multivariable analysis

OR (95% CI)

p value

Base model

OR (95% CI)

p value

Base model + PHI

OR (95% CI)

p value

Age

1.02 (0.98–1.05)

0.2943

1.02 (0.98–1.05)

0.3404

1.02 (0.98–1.06)

0.3068

DRE

1.51 (0.87–2.59)

0.1325

1.61 (0.93–2.81)

0.0855

1.65 (0.94–2.89)

0.0755

PSA

1.06 (1.00–1.11)

0.0311

1.07 (1.01–1.13)

0.0150

1.04 (0.98–1.10)

0.1872

fPSA

0.99 (0.83–1.19)

0.9579

0.88 (0.69–1.12)

0.2901

0.93 (0.73–1.16)

0.4979

p2PSA

0.99 (0.99–1.01)

0.7888

    

%p2PSA

1.03 (0.99–1.06)

0.0666

    

PHI

1.02 (1.01–1.03)

0.0025

  

1.02 (1.00–1.03)

0.0153

  1. DRE digital rectal examination, PSA prostate specific antigen, fPSA free PSA, p2PSA [− 2]proPSA, %p2PSA p2PSA/fPSA ratio, PHI Prostate Health Index, OR Odds ratio, CI confidence interval
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BMC Urology

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