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Table 3 Univariable and multivariable logistic regression model of preoperative variables predicting Gleason sum upgrading

From: Preoperative prostate health index predicts adverse pathology and Gleason score upgrading after radical prostatectomy for prostate cancer

Variables Univariable analysis Multivariable analysis
OR (95% CI) p value Base model
OR (95% CI)
p value Base model + PHI
OR (95% CI)
p value
Age 1.02 (0.98–1.05) 0.2943 1.02 (0.98–1.05) 0.3404 1.02 (0.98–1.06) 0.3068
DRE 1.51 (0.87–2.59) 0.1325 1.61 (0.93–2.81) 0.0855 1.65 (0.94–2.89) 0.0755
PSA 1.06 (1.00–1.11) 0.0311 1.07 (1.01–1.13) 0.0150 1.04 (0.98–1.10) 0.1872
fPSA 0.99 (0.83–1.19) 0.9579 0.88 (0.69–1.12) 0.2901 0.93 (0.73–1.16) 0.4979
p2PSA 0.99 (0.99–1.01) 0.7888     
%p2PSA 1.03 (0.99–1.06) 0.0666     
PHI 1.02 (1.01–1.03) 0.0025    1.02 (1.00–1.03) 0.0153
  1. DRE digital rectal examination, PSA prostate specific antigen, fPSA free PSA, p2PSA [− 2]proPSA, %p2PSA p2PSA/fPSA ratio, PHI Prostate Health Index, OR Odds ratio, CI confidence interval