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Fig. 5 | BMC Urology

Fig. 5

From: Elevated MTA1 induced the migration and invasion of renal cell carcinoma through the NF-κB pathway

Fig. 5

MTA1 regulated the migration and invasion of RCC cells via NF-κB. A498 cells were transfected with pcDNA3.1-Flag, Flag-MTA1, and Flag-MTA1 + PDTC (10 nM). a In the wound healing assay, MTA1 improved the migration of RCC cells, while the addition of the inhibitor PDTC blocked the effect of MTA1 on migration. Scale bar: 100×. b In the transwell assay, MTA1 markedly induced invasion of A498 cells, but compared to the MTA1 group, the invasion of MTA1 + PDTC A498 cells was lower. **p < 0.01; ***p < 0.001; Scale bar: ×40

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