Skip to main content

Table 3 Risk of bias for cohort studies using Newcastle–Ottawa Assessment tools

From: Meta-analysis of neoadjuvant chemotherapy compared to radical cystectomy alone in improving overall survival of muscle-invasive bladder cancer patients

Study

Selection

Comparability

Outcome

Overall

Representativeness of exposed cohort

Selection of nonexposed

Ascertainment of exposure

Outcome not present at start

Study controls for treatment

Assessment of outcome

Adequate follow-up length

Adequacy of follow-up

Lane (2018)

*a

*

*

*

*d

*

*

*

8

Anan (2017)

*b

*

*

*

-

*

*

*

7

Hinata (2017)

*b

*

*

*

*e

*

*

*

8

Martinez-Pineiro (1995)

*b

*

*

*

*f

*

*

*

8

Milenkovic (2018)

-c

*

*

*

-g

*

*

*

6

Mozzane (2019)

*a

*

*

*

*d,e

*

*

*

8

Gronostaj (2019)

-c

*

*

*

-g

*

*

*

6

Boeri (2019)

-a

*

*

*

*e

*

*

*

7

Nitta (2019)

*b

*

*

*

-g

*

*i

*

7

Ploussard (2020)

*b

*

*

*

*

*

*

7

Russell (2019)

*a

*

*

*

*e

*

*

*

8

Vetterlein (2017)

*a

*

*

*

*d

*

*

*

8

Hermans (2019)

*a

*

*

*

-h

*

*

*

7

  1. aNational or international registry
  2. bMore than 1 institution
  3. cSingle institution
  4. dAdjust age, sex, race, and other factors
  5. eAdjust with propensity score matched analyses
  6. fNo significant differences for age, size, and performance status
  7. gNot controlled, age showed significant difference
  8. hNot possible to do propensity score match analysis for potential confounders and important prognostic factor
  9. iSignificant shorter follow-up period in treatment group