Fig. 3

Biomarker staining reveals androgen-intact tumor with NEPC-like marker expression. Serial 3 µm sections from recurrence biopsy sample were stained with antibodies to synaptophysin (SYN), neuron-specific enolase 1 (NSE1), chromogranin (CG), androgen receptor (AR), thyroid transcription factor 1 (TTF1), and CD56. Upper panel indicates ×4 magnification (scale bar = 200 µm) with box indicating lower panel magnification of ×15 (scale bar = 100 µm)