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Fig. 6 | BMC Urology

Fig. 6

From: Immune molecular profiling of a multiresistant primary prostate cancer with a neuroendocrine-like phenotype: a case report

Fig. 6

Gene set enrichment analysis of transcriptomics and proteomics revealed canonical NEPC pathway dysregulation in recurrent tumor tissue. Bubblechart of significant enrichment hits of pathways from a Pathway Interaction Database (PID) and b MSigDB Hallmark database. Red arrows indicating significant hits in both transcriptomics and proteomics. Black arrows indicate pathways regulated by known NEPC drivers. NES: normalized enrichment score, FDR: false discovery rate

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