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Table 2 Risk factors for post-operative delirium

From: Risk factors for incident delirium among urological patients: a systematic review and meta-analysis with GRADE summary of findings

Risk factor

Hamann 2005 [27]

Large 2012 [28]

Tai 2015 [29]

Tognoni 2010 [30]

Gani 2012 [26]

Sato 2016 [32]

Xue 2016 [31]

Demographic factors

Older age*

 = 

 + 

 + 

 + 

 = 

 + 

 + 

Male sex ± 

 = 

 = 

 

 = 

 = 

 = 

 

Married ± 

 

 = 

 = 

   

 = 

Education length in years

   

 = 

  

 = 

Mental status (mean MMSE/mean CDT)

 = 

 + 

 + 

 = / + 

  

 = 

History of delirium ± 

   

 + 

   

Depression (DSI > 40 or GDS)

 = 

 

 + 

 = 

   

Comorbidity (based on mean age-adjusted CCI, CCI > 3 or ≥ 2 co-morbidities)

 = 

 = 

 

 = 

  

 + 

Mean BMI

 

 = 

 = 

  

 = 

 = 

ADL (mean score or functions lost)

 

 = 

 = 

 = 

  

 = 

IADL (mean score or functions lost)

  

 + 

 + 

   

Surgical

Operation time (mean or median)

 + 

 = 

   

 = 

 

Blood loss (mean or median)

 

 = 

   

 = 

 

Intraoperative hypotension ± 

   

 + 

?

 

 = 

GA versus regional Anaesthesia

 = 

  

 = 

 

 = 

 = 

Alcohol intake (active consumption or excess/abuse)

 = 

 = 

 = 

 = 

  

 = 

  1. *Age was described by a variety of methods in the included studies such as mean, median or age range. The results presented represent if increasing age was associated with POD
  2.  ±Proportion of patients with the exposure/risk factor
  3. + increased risk of POD, = no increased risk of POD, ? not clear due to absence of data. See Additional file 1: Table 1 (S1) for full details
  4. MMSE mini mental state examination, CDT clock drawing test, DSI Depression Status Inventory, GDS geriatric depression scale, CCI Charlson Comorbidity Index, BMI body mass index, ADL activities of daily living, IADL Instrumental Activities of Daily Living, GA general anaesthetic, CAGE CAGE questionnaire relates to drinking habits [24]