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Table 1 Clinical and pathological features of all known cases of PPAS

From: Primary pure angiosarcoma of the testis: a vanishingly rare malignancy. Case report and literature review

Case

Age (years)

Diagnosis

Presentation

Investigations

Macroscopic features of testicular lesion

Symptoms (duration)

Patient noticed lump? (duration)

Bloods

Testicular ultrasound

Site

Appearance

Size (mm)

Current case

56

PPAS

Testicular pain, swelling, redness (4 days)

No

Normal

Two lesions Heterogenous, hypoechoic, some cysts, no vascularity

Parenchyma, rete testis, tunica

A: cream-coloured, Solid

B: Haemorrhagic, infiltrative

A: 17 × 17 × 19

B: 20 × 20 × 20

Piotrowski et al. [19]

58

PPAS

Hip pain, back pain (3 months)

No

Normal

Two lesions

A: Parenchyma, epididymis

B: Spermatic cord

N/A

A: 120 × 68 × 68

B: 35 × 24 × 20

Jain et al. [18]

63

PPAS

Testicular enlargement (8 months), preceding testicular firmness (10 years)

Yes (10 years)

Normal

Solid lesion

Parenchyma replaced by tumour

Haemorrhagic, necrotic, focal solid white

110 × 80 × 70

Armah et al. [17]

80

PPAS

Painless lump (2 months), hydrocoele (7 years)

Yes (2 months)

N/A

N/A

Parenchyma, epididymis

Haemorrhagic, solid

30

Mašera et al. [16]

74

PPAS, epithelioid

Fever unknown cause (3 weeks)

No

CRP↑ ESR↑

Transonic, vascularity

Parenchyma

Haemorrhagic, brown-white, infiltrative

17