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Fig. 3 | BMC Urology

Fig. 3

From: Proteomic analysis of bladder biopsies from interstitial cystitis/bladder pain syndrome patients with and without Hunner’s lesions reveals differences in expression of inflammatory and structural proteins

Fig. 3

NDA HIC tissues exhibited increased expression of immune response proteins, with decreased protein expression for Rap1 signaling and general metabolism. Association map for proteins differentially expressed in NDA Hunner’s IC biopsies compared to NDA non-Hunner’s IC biopsies. Nodes in the green box were increased in NDA HIC samples, while nodes in the red box were decreased. White nodes represent immune response proteins, while blue and red nodes represent protein metabolism and Rap1 signaling proteins, respectively. Lines between nodes indicate reported associations as detailed in “Methods” section

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