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Table 2 EORTC QLQ-C30 and EQ-5D-5L compliance rates from baseline through cycle 8 and 30-day follow-up (ITT population)

From: Health-related quality of life in the randomized phase 3 study of ramucirumab plus docetaxel versus placebo plus docetaxel in platinum-refractory advanced urothelial carcinoma (RANGE)

Assessment time point

QLQ-C30

EQ-5D-5L

RAM + DOC

(n = 263)

PL + DOC

(n = 267)

RAM + DOC

(n = 263)

PL + DOC

(n = 267)

Baseline

254/263 (97)

260/267 (97)

254/263 (97)

260/267 (97)

Cycle 1

214/229 (93)

226/237 (95)

212/229 (93)

225/237 (95)

Cycle 2

159/165 (96)

159/165 (96)

158/165 (96)

159/165 (96)

Cycle 3

139/147 (95)

133/138 (96)

136/147 (93)

133/138 (96)

Cycle 4

114/126 (90)

100/105 (95)

114/126 (90)

100/105 (95)

Cycle 5

108/114 (95)

88/94 (94)

107/114 (94)

88/94 (94)

Cycle 6

79/87 (91)

64/71 (90)

83/87 (95)

63/71 (89)

Cycle 7

64/68 (94)

52/59 (88)

66/68 (97)

52/59 (88)

Cycle 8

52/56 (93)

36/41 (88)

51/56 (91)

36/41 (88)

Follow-up

116/215 (54)

119/231 (52)

113/215 (53)

121/231 (52)

  1. DOC docetaxel, EORTC QLQ-C30 European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30, EQ-5D-5L EuroQoL five-dimensions, ITT intention-to-treat, PL placebo, RAM ramucirumab
  2. Data are presented as number/total number (%)
  3. For compliance, the total number is the number expected to complete at the assessment time point
  4. On-treatment compliance reporting is truncated at cycle 8, but similar rates were reported for later cycles
  5. The median number of cycles administered in both treatment arms was 4