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Fig. 2 | BMC Urology

Fig. 2

From: Role of microRNA-381 in bladder cancer growth and metastasis with the involvement of BMI1 and the Rho/ROCK axis

Fig. 2

miR-381 inhibits malignant behaviors of BCa cells. a miR-381 expression in cells after miR-381 mimic transfection detected by RT-qPCR, and it was found that miR-381 mimic#2 showed the best efficacy (*pā€‰<ā€‰0.05, two-way ANOVA); b optical density at 450Ā nm measured by two-way ANOVA (*pā€‰<ā€‰0.05, two-way ANOVA); c migration rate of each group of cells at the 24th h (*pā€‰<ā€‰0.05, two-way ANOVA); d invasion rate of each group of cells measured by transwell assay (*pā€‰<ā€‰0.05, two-way ANOVA); e apoptosis rate of cells determined by flow cytometry (*pā€‰<ā€‰0.05, two-way ANOVA); f tumor volume change and weight on the 28th day after implantation of cells transfected miR-381 mimic (*pā€‰<ā€‰0.05, two-way ANOVA); Repetitionā€‰=ā€‰3

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