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Fig. 4 | BMC Urology

Fig. 4

From: Role of microRNA-381 in bladder cancer growth and metastasis with the involvement of BMI1 and the Rho/ROCK axis

Fig. 4

Overexpression of BMI1 promotes BCa progression. a optical density at 450 nm of each group of cells according the CCK-8 method (*p < 0.05, two-way ANOVA); b migration distance at the 24th hour measured by the scratch test (*p < 0.05, two-way ANOVA); c number of invaded cells at the 24th hour determined by the transwell assay (*p < 0.05, two-way ANOVA); d number of PI-Annexin V-double positive cells detected by flow cytometry (*p < 0.05, two-way ANOVA); e tumor growth rate change and weight on the 28th day in nude mice (n = 8) (*p < 0.05, two-way ANOVA); Repetition = 3

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