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Table 3 Cross analysis (chi-square) with Fisher’s exact test

From: Optimal treatment for penile verrucous carcinoma: a systematic literature review

 

Operation

Total

χ2

(p)

Less aggressive treatment

Aggressive

treatment

Tumor location

Glans

Case

11

22

33

2.532

(.686)

  

%

55.0%

57.9%

56.9%

 
 

Coronoid

sulcus involvement

Case

4

6

10

 
 

%

20.0%

15.8%

17.2%

 

Stage

Ta

Case

17

35

52

.713

(.405)

%

85.0%

92.1%

89.7%

T1

Case

3

3

6

%

15.0%

7.9%

10.3%

Adjuvant treatment

none

Case

8

35

43

21.926**

(.000)

%

40.0%

92.1%

74.1%

Radiotherapy

Case

0

1

1

%

0.0%

2.6%

1.7%

Chemotherapy

Case

4

2

6

%

20.0%

5.3%

10.3%

Chemoradiotherapy

Case

2

0

2

%

10.0%

0.0%

3.4%

Local therapy

Case

6

0

6

%

30.0%

0.0%

10.3%

Recurrence

No

Case

17

34

51

.247

(.619)

%

85.0%

89.5%

87.9%

Yes

Case

3

4

7

%

15.0%

10.5%

12.1%

Treatment trends over time following the year of issue

1970s

Case

1

0

1

12.549**

(.005)

%

5.0%

0.0%

1.7%

1980s

Case

2

12

14

%

10.0%

31.6%

24.1%

1990s

Case

1

1

2

%

5.0%

2.6%

3.4%

2000s

Case

10

5

15

%

50.0%

13.2%

25.9%

2010s

Case

6

20

26

%

30.0%

52.6%

44.8%

  1. *p < 0.05, **p < 0.01