Efficacy of dapoxetine treatment in Chinese patients with premature ejaculation and possible factors affecting efficacy in the real-world practice

Table 1 Possible factors affecting the efficacy of dapoxetine 30 mg treatment for 4 weeks

Parameters	CGIC-C		P
Parameters	0 (n = 46)	≥1 (n = 108)	P
Age (yeas, mean ± SD)	33.8 ± 8.1	31.9 ± 6.1	0.213
Marital Status: Married	88.6%	84.5%	0.508
PE duration (years, mean ± SD)	6.4 ± 5.7	8.2 ± 6.8	0.058
Type of PE (% of primary PE)	84.8%	70.4%	0.060
Percentage of Intercourse frequency ≥ 2 times	43.4%	53.7%	0.245
Percentage of CP	41.3%	41.7%	0.967
Percentage of previous SSRI use	10.9%	18.5%	0.239
Percentage of previous Effective SSRI use	10.0%	28.6%	0.097
Percentage of history of Circumcision or penile dorsal nerve transection	28.3%	34.3%	0.467
PHQ-9(median [min, max])	6.0 [0, 27]	6.0 [0, 26]	0.835
GAD-7(median [min, max])	4.0 [0, 25]	3.5 [0, 21]	0.253
IELT (Seconds, mean ± SD)	56.3 ± 44.4	63.0 ± 42.5	0.262
NITBE (times, mean ± SD)	28.0 ± 22.0	41.5 ± 30.1	0.010^*
PEDT (mean ± SD)	15.7 ± 2.7	14.5 ± 2.6	0.009^*

CGIC Clinical Global Impression of Change, CP chronic prostatitis, ED erectile dysfunction, GAD-7 General Anxiety Disorder Questionnaire, IELT intravaginal ejaculatory latency time, NITBE number of intravaginal thrusts before ejaculation, PE premature ejaculation, PEDT Premature Ejaculation Diagnostic Tool, PHQ-9 Patient Health Questionnaire-9 items, SD standard deviation, SSRI selective serotonin reuptake inhibitors
^*statistical significance

ISSN: 1471-2490