Skip to main content

Table 4 Multivariate Cox regression analysis of blood parameter with clinicopathologic characteristics and SSIGN prognostic model

From: Preoperative anaemia and thrombocytosis predict adverse prognosis in non‐metastatic renal cell carcinoma with tumour thrombus

Variable

Overall survival

Progression-free survival

HR

95 %CL

P

HR

95 %CL

P

Model 1

Age1,2

/

/

NS

/

/

NS

Symptom at presentation1,2

/

/

NS

/

/

NS

Histologic subtype1,2

CCRCC

Ref

  

Ref

  

Non-CCRCC

/

/

NS

2.835

1.403–5.728

0.004

Nuclear grade1,2

I–II

Ref

  

Ref

  

III–IV

/

/

NS

2.069

1.059–4.039

0.033

Lymph node metastasis1,2

4.811

1.365–16.961

0.015

5.739

2.136–15.420

0.001

Necrosis2

/

/

/

/

/

NS

Blood parameters

PLR2

/

/

/

/

/

NS

Thrombocytosis1,2

/

/

NS

2.324

1.215–4.446

0.011

Anaemia1,2

2.873

1.310–6.299

0.008

/

/

NS

Model 2

SSIGN score

Low-risk (score 2–4)

Ref

  

Ref

  

Intermediate-risk (score 5–7)

1.447

0.499–4.193

0.496

1.833

0.871–3.858

0.111

High-risk (score 8–11)

5.847

1.838–18.603

0.003

3.025

1.230–7.436

0.016

Blood parameters

PLR2

/

/

/

/

/

NS

Thrombocytosis1,2

/

/

NS

2.375

1.245–4.469

0.008

Anaemia1,2

3.453

1.495–7.978

0.004

/

/

NS

  1. NS not statistically significant
  2. 1The variable that was selected into the multivariate model correlated with overall survival
  3. 2The variable that was selected into the multivariate model correlated with progression-free survival