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Table 3 CTC counts of aneuploidy of chromosome 8 and/or 7 from blood samples

From: CTCs detection from intraoperative salvaged blood in RCC–IVC thrombus patients by negative enrichment and iFISH identification: a preliminary study

Case

Sample

CTC counts

Triploid of chromosome 8

Tetraploid of chromosome 8

Polydiploid (> 4) of chromosome 8

Triploid of chromosome 7

Tetraploid of chromosome 7

Polydiploid (> 4) of chromosome 7

Polydiploidy chromosome of both 7 and 8

CTM

Sum

Total number

1

S1

3

       

3

 

S2

          

S3

1

       

1

 

S4

          
          

4

2

S1

1

  

2

  

1a

 

4

 
 

S2

          
 

S3

   

1

    

1

 
 

S4

          
           

5

3

S1

6

1

 

3

    

10

 

S2

1

  

1

   

1

3

 

S3

          

S4

          
          

13

4

S1

4

  

3

    

7

 

S2

3

  

1

  

1a

 

5

 

S3

          

S4

          
          

12

5

S1

1

  

1

  

1a

 

3

 

S2

   

1

    

1

 

S3

          

S4

          
          

5

  1. Tumor cells were recognized and counted using immunostaining and fluorescence in situ hybridization technology. Only cells with CD45−/DAPI+/CEP8+ (> 2), CD45−/DAPI+/CEP8+ (> 2), and CD45−/DAPI+/CEP8+ and CEP7+ (hyperdiploidy) were identified as CTCs
  2. Number 0 were not shown in the table
  3. S1, peripheral venous blood sample from internal jugular vein before skin incision, indicative of the circulating tumor cells; S2, blood sampled in the vena cava around thrombus during surgery, indicating direct cells shedding in surgical manipulation; S3, blood after IOCS washing and before LDF filtering, which represents the tumor cell cleaning efficacy with only IOCS; S4, blood sampled after LDF filtration, meaning the actual final filtering result after IOCS–LDF
  4. CTM circulating tumor microemboli
  5. aTriploid of both chromosome 8 and 7
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BMC Urology

ISSN: 1471-2490

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