Table 5 Gene ontology summary including AP-2 factors subdivision for the most significant groups from DFS analysis
Transcription factor | Cluster number | Examples of genes | Biological process | Statistical significance (p value ) |
|---|---|---|---|---|
AP-2α | 1 | AMOT; SEMA5A | Regulation of cell migration | 0.0258 |
2 | PLXNA4; PCDHGB7; DLG2; CDHR3; PCDHGB6; PCDHGB5; PCDHGA7 | Cell adhesion | 0.00264 | |
7 | EYA2 | Positive regulation of DNA repair | 0.0222 | |
11 | NTNG2 | Cell motility | 0.0344 | |
12 | BEGAIN; NTF4; GRB14; WNT2B; HOMER2; INHA | Cell surface receptor signaling pathway | 0.0257 | |
13 | PDCD1LG2 | Positive regulation of T cell proliferation | 0.0161 | |
AP-2γ | 0 | COL4A6; STK32B; WNK2 | Cell communication | 0.0133 |
1 | PLEKHB1; SEMA5A; GATA3 | Regulation of cell differentiation | 0.0145 | |
3 | CASS4 | Cell migration | 0.0329 | |
5 | DSP; PKP1; L1CAM; CELSR2 | Cell–cell adhesion | 0.000683 | |
7 | TLE2; SFRP1 | Negative regulation of canonical Wnt signaling pathway | 0.0146 | |
12 | ZBP1 | Type I interferon signaling pathway | 0.00902 |