Skip to main content
Fig. 3 | BMC Urology

Fig. 3

From: Sensitizing the cytotoxic action of Docetaxel induced by Pentoxifylline in a PC3 prostate cancer cell line

Fig. 3

Caspase activation in PC3 tumor cells treated with PTX, DTX or their combination. The 2 × 105 PC3 cells were cultured and exposed to DTX 25 nM, PTX 8 mM, or PTX 8 mM + DTX 25 nM for 24 h. a General caspase activity was determined by flow cytometry. b Caspases-3, -8, and -9 activity was determined by sandwich ELISA assay. The results were normalized in relation to UCG, and represent the mean ± SD of the three experiments carried out in triplicate. Statistical analysis: Mann‒Whitney U test *(p < 0.05) versus UCG, + (p < 0.05) versus DTX 25 nM

Back to article page