Fig. 4
Senescent PC3 cells treated with DTX, PTX or their combination. The 1 × 106 PC3 cells were cultured and treated with DTX 25 nM, PTX 8 mM, or PTX 8 mM + DTX 25 nM for 48 h. Cell senescence was determined by the levels of the β-galactosidase enzyme by flow cytometry. UCG = Untreated Control Group, ADM = Adriamycin (ADM) use as a positive control. The results represent the mean ± SD of the three replicated experiments. Statistical analysis: Mann‒Whitney U test *(p < 0.05) versus UCG, + (p < 0.05) versus DTX 25 nM