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Fig. 2 | BMC Urology

Fig. 2

From: MicroRNA-4429 suppresses proliferation of prostate cancer cells by targeting distal-less homeobox 1 and inactivating the Wnt/β-catenin pathway

Fig. 2

miR-4429 mimic suppresses the biological activity of PCa cells. a miR-4429 expression in DU145 and PC-3 cells introduced with miR-4429 mimic/miR-4429 inhibitor determined by RT-qPCR (unpaired t test, P < 0.0001). b PCa cell proliferation in DU145 and PC-3 cells introduced with miR-4429 mimic/miR-4429 inhibitor determined by CCK-8 assay (two-way ANOVA, P < 0.0001). c Number of colonies in DU145 and PC-3 cells introduced with miR-4429 mimic/miR-4429 inhibitor determined by colony formation assay (one-way ANOVA, P < 0.0001). d Apoptosis in DU145 and PC-3 cells introduced with miR-4429 mimic/miR-4429 inhibitor determined by flow cytometry (one-way ANOVA, P < 0.0001). e Invasion ability in DU145 and PC-3 cells introduced with miR-4429 mimic/miR-4429 inhibitor determined by Transwell assay (one-way ANOVA, P < 0.0001). Data were expressed as mean ± SD from three independent experiments. *P < 0.05 was considered to show statistical significance

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BMC Urology

ISSN: 1471-2490

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