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Table 6 Poisson regression sensitivity analysis of symptomatic UTIs by number of UTI prior to enrolment

From: High dose versus low dose standardized cranberry proanthocyanidin extract for the prevention of recurrent urinary tract infection in healthy women: a double-blind randomized controlled trial

 

Low dose group, 2 × 1 mg PAC

High dose group, 2 × 18.5 mg PAC

Incidence rate ratio (95% CI)

p value

Participants with less than 5 UTIs in the 12 months preceding enrolment

n = 46

n = 51

 

Number of symptomatic UTI

39

21

 

Symptomatic UTI, age-adjusted incidence density (95% CI)a

2.29 (1.66–3.16)

1.32 (0.81–2.13)

0.57 (0.33–0.99)

p = 0.048

Participants with 5 UTIs or more in the 12 months preceding enrolment

n = 27

n = 21

 

Number of symptomatic UTI

20

24

 

Symptomatic UTI, age-adjusted incidence density (95% CI)a

2.23 (1.37–3.61)

3.34 (1.96–5.68)

1.50 (0.81–2.76)

p = 0.195

  1. aIncidence rate ratios and p value for symptomatic UTIs per woman-year of observation by number of UTI in the 12 months prior to enrolment (less than 5 UTIs vs greater than 5 UTIs) and adjusted for age group (< 45 years vs ≥ 45 year)