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Table 1 Definitions of incident benign prostatic hyperplasia (BPH)-related outcomes and nocturia

From: Body size throughout the life-course and incident benign prostatic hyperplasia-related outcomes and nocturia

  Nocturia Physician diagnosis Finasteride use Prostate volume ≥ 30 cc PSA elevation
Baseline questionnaire      
Wake 2 + times/night to urinate during a typical night in the past year? (Nocturia)  ×   ×   ×   ×   × 
Ever been told by a doctor that they have an enlarged prostate or BPH?  ×   ×   ×   ×   × 
Ever had TURP or prostatectomy for benign disease?  ×   ×   ×   ×   × 
Baseline examination      
Prostate volumea ≥ 30 cc  ×   ×   ×   ×   × 
PSA > 1.4 ng/mL and no known cancer  ×   ×   ×   ×   × 
Supplemental questionnaire      
Wake 2 + times/night to urinate during a typical night in the past year? (Nocturia)  *     
Ever been told by a doctor that they have an enlarged prostate or BPH?     
Annual study update      
Taken Proscar or Propecia (Finasteride) in the past year?  ×     *  ×   × 
Follow-up examination      
Prostate volumea ≥ 30 cc on any of three DREs      *  
PSA > 1.4 ng/mL on any one of five PSA tests       *
Total 1515 1446 881 2499 1322
  1.  × = exclusion criteria; * = inclusion criteria; DRE = digital rectal examination; PSA = prostate-specific antigen
  2. aCalculated as (π/6) × width2 × length, where width is the transverse measurement and length is the sagittal measurement. Both measurements were estimated by palpation by the trained DRE examiner