Table 4 Age-adjusted risk ratios (RRs) and 95% confidence intervals (CIs) of incident benign prostatic hyperplasia (BPH)-related outcomes and nocturia by body mass index (BMI) change across the life-course; Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

BMI at 20 (kg/m²)

 < 25

Nocturia^a

1.00

Referent

1.09

0.98, 1.22

1.28

1.10, 1.47

No. of cases

336

609

179

Prostate volume ≥ 30 cc^b

1.00

Referent

1.12

1.05, 1.20

1.04

0.94, 1.15

No. of cases

572

1058

241

25–29

Nocturia^a

1.40

1.03, 1.90

1.09

0.93, 1.28

1.25

1.08, 1.45

No. of cases

26

150

177

Prostate volume ≥ 30 cc^b

0.94

0.73, 1.20

1.16

1.06, 1.26

1.10

1.00, 1.21

No. of cases

31

280

255

 ≥ 30

Nocturia^a

^c

^c

1.41

1.07, 1.86

No. of cases

33

Prostate volume ≥ 30 cc^b

^c

1.61

1.32, 1.97

1.25

1.05, 1.48

No. of cases

13

48

BMI at 50 (kg/m²)

 < 25

Nocturia^a

1.00

Referent

1.09

0.93, 1.28

^c

No. of cases

317

158

Prostate volume ≥ 30 cc^b

1.00

Referent

1.07

0.98, 1.18

^c

No. of cases

539

253

25–29

Nocturia^a

1.04

0.80, 1.34

1.06

0.94, 1.19

1.30

1.13, 1.49

No. of cases

44

561

189

Prostate volume ≥ 30 cc^b

0.87

0.72, 1.05

1.13

1.06, 1.21

1.06

0.96, 1.17

No. of cases

60

1029

252

 ≥ 30

Nocturia^a

^c

1.23

0.96, 1.58

1.21

1.05, 1.41

No. of cases

44

195

Prostate volume ≥ 30 cc^b

^c

1.16

1.00, 1.36

1.10

1.00, 1.21

No. of cases

69

288