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Table 3 Previous studies describing use of ALA-PDT/PDD to diagnose UT-UC

From: Photodynamic diagnostic ureteroscopy using the VISERA ELITE video system for diagnosis of upper-urinary tract urothelial carcinoma: a prospective cohort pilot study

References Country Study design Objective Sample size Video system supplier Sensitivity (%) Specificity (%)
Waidelich [17] Germany Pilot study PDTa 4 Not stated
Somani et al. [18] UK Pilot study PDDb 4 Karl Storz
Audenet et al. [19] France Review
Ahmad et al. [20] UK Prospective cohort PDD 26 Karl Storz 100 62.5
Aboumarzouk et al. [21] UK Prospective cohort PDD 32 Karl Storz 96 100
Aboumarzouk et al. [22] UK Prospective cohort PDD 30 Karl Storz 94 100
Bondad et al. [25] UK Retrospective Unknown 24
Kata et al. [9] UK Review PDD Karl Storz
Kata et al. [10] UK Prospective cohort PDD 54 Karl Storz 95.8 96.6
Osman et al. [7] Bahrain Review
This study (2019) Japan Prospective cohort PDD 20 VISERA ELITE, Olympus 62.5 67.3%
  1. aPDT photodynamic therapy
  2. bPDD photodynamic diagnosis