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Fig. 7 | BMC Urology

Fig. 7

From: Let-7i-5p enhances cell proliferation, migration and invasion of ccRCC by targeting HABP4

Fig. 7

HABP4 was modulated by let-7i-5p. a Schematic diagram of the let-7i-5p binding sites within the 3′-UTR of HABP4 mRNA (WT-HABP4) and mutated sequences (Mut-HABP4). The mutated HABP4 3′-UTR sequence is presented in red. b Luciferase assay of 786-0 and 769-P cells after co-transfection with WT or Mut HABP4 3′-UTR and the let-7i-5p mimic. c 786-0 and 769-P cells were transfected with the let-7i-5p mimic, let-7i-5p inhibitor, and corresponding NCs and incubated for 72 h. Cells were harvested and assayed using qRT-PCR. d Correlation between HABP4 expression and let-7i-5p in the TCGA database. Data are presented as mean ± SD. ns > 0.05; **P < 0.01; ***P < 0.001

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