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Table 3 Univariate and multivariate logistic regression analysis to predict pathologic significant Gleason score upgrading (≥ 4 + 3)

From: Favorable intermediate risk prostate cancer with biopsy Gleason score of 6

 

Univariate analysis

Multivariate analysis

OR

95%CI

p-value

OR

95%CI

p-value

Age

1.000

0.950–1.053

0.998

   

Bdoy mass index

1.092

0.958–1.245

0.186

   

DM

0.937

0.303–2.892

0.909

   

HTN

1.273

0.645–2.515

0.486

   

Prostate volume

0.981

0.960–1.003

0.087

   

PSA

0.936

0.824–1.063

0.310

   

PSA density

2.755

0.352–21.536

0.334

   

PIRADS (< 3 vs. ≥ 3)

6.940

2.788–17.275

 < 0.001

6.246

2.400–16.255

 < 0.001

Number of biopsy (12 vs. ≥ 13)

0.319

0.093–1.099

0.070

   

Mean percentage of positive core

1.007

0.990–1.025

0.431

   

Mean tumor length

3.667

1.493–9.005

0.005

0.133

0.014–1.285

0.081

Mean percentage of total tumor of core

1.027

1.012–1.041

 < 0.001

1.049

1.014–1.086

0.006