Fig. 6
From: Expression patterns of the immune checkpoint ligand CD276 in urothelial carcinoma
CD276 expression in normal appearing urothelium from bladder tumor patients. Expression of CD276 was evaluated by immunohistochemistry in areas presenting with normal histology and samples obtained from patients at earlier (< pT3a) versus later T stages (≥ pT3a) were compared. In confirmed normal urothelium from patients of tumor stages < pT3a, CD276 expression scored with a median of 80. In confirmed normal urothelium from tumor patients at stages ≥ pT3a CD276 dropped significantly to a median of 40