Table 2 Pathological data from previous cases and the present case of glomus tumor in the bladder
From: Unusual glomus tumor of the bladder: a rare case report and literature review
Case No | Authors and reference | Pathologic features | Immunohistochemically stains | |
|---|---|---|---|---|
Positive | Negative | |||
1 | Shim et al4 | A large number of tumor cells had infiltrated into the subepithelial connective tissues and proper muscles, which were primarily perivascular in distribution. The cells showed diffuse cytologic atypia with spindle morphology and marked nuclear atypia with high mitotic activity (50/10HPF); Multifocal tumor necrosis and hemorrhage were also noted | SMA | Cytokeratins, Epithelial membrane antigen, S100 protein, Desmin, CD31, CD34 |
2 | Tripodi et al3 | The neoplasm was well circumscribed and composed of nests of monomorphic cells with bland nuclei and eosinophilic cytoplasm. Atypia, mitoses, intravascular growth, and necrosis were absent | SMA, CD34 | p63, Cytokeratin AE1/AE3 |
3 | Lindsay et al5 | Abnormal proliferation of ovoid cells in the lamina propria, uniform ovoid nuclei with indistinct eosinophilic cytoplasm, sheet-like growth pattern with a prominent capillary network, mild nuclear atypia and mototic index accounted to 2 mitosis/HPF | SMA, Smooth muscle myosin | CD 34 |
4 | Palmisano et al2 | The neoplasm was composed of uniform small oval to spindle cells, without nuclear atypias, disposed in a vaguely storiform pattern, separated by a vascular stroma; numerous cells with bizarre nuclei were scattered throughout the lesion; mototic index accounted to 2 mitosis/50HPF | SMA, Vimentin, bcl-2 | Citokeratins, p63, Desmin, Calponin, CD34, S100, HMB-45, CD68R, c-kit, DOG-1, ALK-1, Chromogranin, a-Inhibin |
5 | Jiwei et al. (present case) | The tumor cells were uniform small oval and clustered around dilated vessels. Atypia, mitoses, intravascular growth, and necrosis were absent | SMA, Vimentin | Desmin |