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Table 2 Population demographic and clinical characteristics for female sub-cohorts

From: The use of mono- and combination drug therapy in men and women with lower urinary tract symptoms (LUTS) in the UK: a retrospective observational study

  

LUTS (including OAB) N = 29,094

SUI N = 1688

Age at index date

n

29,094

1688

 

Mean (SD)

62.92 (16.77)

54.24 (16.29)

 

18–24

604 (2.1%)

32 (1.9%)

 

25–34

1121 (3.9%)

159 (9.4%)

 

35–44

2536 (8.7%)

315 (18.7%)

 

45–54

4835 (16.6%)

399 (23.6%)

 

55–64

5264 (18.1%)

315 (18.7%)

 

65–74

6446 (22.2%)

248 (14.7%)

 

≥ 75

8288 (28.5%)

220 (13.0%)

Index of multiple deprivation at index prescription (GP surgery level)

n

11,999

665

 

1 = least deprived

1534 (12.8%)

86 (12.9%)

 

2

2418 (20.2%)

148 (22.3%)

 

3

2292 (19.1%)

137 (20.6%)

 

4

2285 (19.0%)

105 (15.8%)

 

5 = most deprived

3470 (28.9%)

189 (28.4%)

New comorbidities

n

29,094

1688

Count of newly diagnosed chronic diseases from the QOF within the 12-month pre-index period

Mean (SD)

0.20 (0.48)

0.23 (0.53)

 

0

24,327 (83.6%)

1374 (81.4%)

 

1

3950 (13.6%)

248 (14.7%)

 

2

712 (2.4%)

56 (3.3%)

 

3+

105 (0.4%)

10 (0.6%)

Polypharmacy

n

29,094

1688

Number of distinct BNF headers within the 12-month pre-index period

Mean (SD)

10.77 (7.49)

11.55 (7.42)

 

0

681 (2.3%)

29 (1.7%)

 

[1; 3]

3766 (12.9%)

165 (9.8%)

 

[4; 7]

6944 (23.9%)

384 (22.7%)

 

[8; 19]

14,178 (48.7%)

873 (51.7%)

 

20+

3525 (12.1%)

237 (14.0%)

Antimuscarinic treatment experience within the 12-month pre-index period

n

29,094

1688

 

Yes

2681 (9.2%)

56 (3.3%)

 

No

26,413 (90.8%)

1632 (96.7%)

  1. Female LUTS (including OAB) sub-cohort patients were those receiving an OAB drug (antimuscarinic and/or mirabegron) with or without a SUI drug (duloxetine). Female SUI sub-cohort patients were those receiving duloxetine without an OAB drug. Percentages may not total exactly 100 due to rounding
  2. BNF: British National Formulary; GP: general practitioner; LUTS: lower urinary tract symptoms; OAB: overactive bladder; QOF: Quality and Outcomes Framework; SD: standard deviation; SUI: stress urinary incontinence