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Table 1 Baseline demographics of overall prostate cancer patients and comparison between TPL and non-TPL groups

From: The effect of subsequent immunosuppressant use in organ-transplanted patients on prostate cancer incidence: a retrospective analysis using the Korean National Health Insurance Database

Parameter

Total TPL (N = 51,880)

Non-TPL group (N = 38,910)

TPL group (N = 12,970)

p value

N (%)

N (%)

N (%)

Age (years; mean, STD)

48.10 (10.24)

48.1 ± 10.24

48.1 ± 10.24

1.000

Age, 20 ≤ Age < 50

25,856 (49.84)

19,392 (49.84)

6464 (49.84)

1.000

 50 ≤ Age < 65

24,308 (93.41)

18,231 (93.41)

6077 (93.41)

 

 65 ≤ Age ≤ 75

1,688 (6.49)

1266 (6.49)

422 (6.49)

 

 75 < Age

28 (0.11)

21 (0.11)

7 (0.11)

 

Diagnostic Year of Prostate Cancer

 < .001

   

 2007–2009

1 (0.53)

0 (0)

1 (1.3)

 

 2010–2012

40 (21.28)

20 (18.02)

20 (25.97)

 

 2013–2015

147 (78.19)

91 (81.98)

56 (72.73)

 

Year of transplanted surgery

1.000

   

 2003–2007

12,524 (24.14)

9393 (24.14)

3131 (24.14)

 

 2008–2012

18,532 (35.72)

13,899 (35.72)

4633 (35.72)

 

 2013–2015

20,824 (40.14)

15,618 (40.14)

5206 (40.14)

 

Underlying disease

    

 Hypertension

15,511 (29.90)

7376 (18.96)

8135 (62.72)

< .0001

 Diabetes

9,504 (18.32)

3253 (8.36)

6251 (48.2)

< .0001

 Dyslipidemia

8,546 (16.47)

4461 (11.46)

4085 (31.5)

< .0001

Medication

    

 Aspirin

1776 (3.42)

803 (2.06)

973 (7.5)

< .0001

 Statin

8701 (16.77)

4389 (11.28)

4312 (33.25)

< .0001

 Use of Immunosuppressant agents

21,578 (41.59)

8623 (22.16)

12,955 (99.88)

< .0001

 Duration of immunosuppressant, ≥ 300 days

11,338 (21.9)

225 (0.6%)

11,113 (85.68)

< 0.001

Transplanted organ

    

 1. Kidney

7,026 (13.54)

N.A

7026 (54.17)

 

 2. Liver

5,445 (10.50)

N.A

5445 (41.98)

 

 3. Pancreas

28 (0.05)

N.A

28 (0.22)

 

 4. Heart

398 (0.77)

N.A

398 (3.07)

 

 5. Lung

73 (0.14)

N.A

73 (0.56)

 

Charlson Comordity Index Grade 2

 < 0.001

   

 0

23,693 (45.67)

23,689 (60.88)

4 (0.03)

 

 1

8,231 (15.87)

8126 (20.88)

105 (0.81)

 

 2 or more

19,956 (38.47)

7095 (18.23)

12,861 (99.16)

 

 Survival, alive

50,199 (96.61)

38,092 (97.90)

12,027 (92.73)

< 0.001

 Survival time (year; mean SD)

4.86 (2.49)

4.9 ± 2.49

4.73 ± 2.49

 
  1. N.A not available