Table 2 Univariate and multivariate cox regression for prostate cancer incidence among overall patients
Characteristics | N | Event | Duration | IR (per 1000) | Univariate | Multivariate | ||
|---|---|---|---|---|---|---|---|---|
HR | p value | HR | p value | |||||
Age (years), 20 ≤ Age < 50 | 25,856 | 18 | 135,209.95 | 0.1331 | 0.098 (0.06,0.161) | < .0001 | 0.113 (0.069,0.186) | < .0001 |
50 ≤ Age < 65 | 24,308 | 144 | 110,258.86 | 1.306 | 1 (Ref.) | 1 (Ref.) | ||
65 ≤ Age ≤ 75 | 1688 | 25 | 6550.21 | 3.8167 | 3.089 (2.019, 4.726) | 2.995 (1.948,4.603) | ||
75 < Age | 28 | 1 | 76.54 | 13.0646 | 12.92 (1.803,92.597) | 13.851 (1.918,100.017) | ||
Aspirin | 1776 | 13 | 8017.85 | 1.62138 | 2.3 (1.309,4.04) | 0.0038 | 1.295 (0.722,2.324) | 0.3863 |
Statin | 8701 | 37 | 39,075.1 | 0.94689 | 1.364 (0.952,1.955) | 0.0905 | 1.32 (0.774,2.254) | 0.3082 |
Duration of Immunosuppressant agent (> 300 days) | 11,338 | 78 | 57,837.55 | 1.3486 | 2.345 (1.754,3.134) | < 0.001 | 3.504 (1.345,9.129) | 0.0084 |
Hypertension | 15,511 | 80 | 72,050.92 | 1.11033 | 1.878 (1.407,2.508) | < 0.001 | 1.347 (0.971,1.87) | 0.0746 |
Diabetes mellitus | 9504 | 64 | 44,114.7 | 1.45076 | 2.461 (1.82,3.328) | < 0.001 | 1.198 (0.839,1.71) | 0.3202 |
Dyslipidemia | 8546 | 29 | 37,485.7 | 0.77363 | 1.073 (0.722,1.595) | 0.7258 | 0.632 (0.353,1.131) | 0.122 |
Transplanted organ | ||||||||
Control | 38,910 | 111 | 190,764.2 | 0.58187 | 1 (Ref.) | < .0001 | 1 (Ref.) | 0.0271 |
1. Kidney | 7026 | 21 | 33,615.34 | 0.62471 | 1.08 (0.677,1.722) | 0.319 (0.11,0.922) | ||
2. Liver | 5445 | 54 | 25,616.58 | 2.10801 | 3.661 (2.645,5.068) | 0.838 (0.314,2.24) | ||
3. Pancreas | 28 | 0 | 105.38 | 0 | N.A | N.A | ||
4. Heart | 398 | 2 | 1760.07 | 1.13632 | 2.013 (0.497,8.151) | 0.37 (0.068,2.03) | ||
5. Lung | 73 | 0 | 233.99 | 0 | N.A | N.A | ||