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Table 3 Univariate and Multivariate cox regression for prostate cancer incidence only among organ-transplanted patients

From: The effect of subsequent immunosuppressant use in organ-transplanted patients on prostate cancer incidence: a retrospective analysis using the Korean National Health Insurance Database

Characteristics N Event Duration IR (per 1000) Univariate Multivariate
HR p value HR p value
Age (years), 20 ≤ Age < 50 6464 7 33,223.01 0.2107 0.088 (0.04,0.192) < 0.001 0.111 (0.05,0.245) < 0.001
50 ≤ Age < 65 6077 61 26,552.55 2.29733 1 (Ref.)   1 (Ref.)  
65 ≤ Age ≤ 75 422 9 1537.49 5.85368 2.7 (1.339,5.444)   2.809 (1.383,5.708)  
75 < Age 7 0 18.31 0 0 (0)   0 (0)  
Aspirin Yes 973 7 4371.79 1.60118 1.318 (0.606,2.866) 0.486 1.249 (0.568,2.749) 0.5798
Statin Yes 4312 15 19,924.96 0.75282 0.502 (0.286,0.883) 0.017 1.088 (0.513,2.306) 0.8257
Duration of Immunosuppressant (> 300 days) 11,113 74 56,759.46 1.30375 1.508 (0.473,4.809) 0.488 1.857 (0.581,5.937) 0.2967
Hypertension Yes 8135 40 38,322.42 1.04378 0.648 (0.414,1.013) 0.057 1.213 (0.72,2.043) 0.4685
Diabetes mellitus Yes 6251 48 29,495.66 1.62736 1.79 (1.129,2.838) 0.013 1.296 (0.814,2.063) 0.2747
Dyslipidemia Yes 4085 10 18,540.27 0.53937 0.346 (0.178,0.673) 0.002 0.453 (0.19,1.079) 0.0739
Transplanted organ         
 1. Kidney 7026 21 33,615.34 0.62471 1 (Ref.) 0.0001 1 (Ref.) 0.3227
 2. Liver 5445 54 25,616.58 2.10801 3.398 (2.053,5.626)   2.016 (1.067,3.809)  
 3. Pancreas 28 0 105.38 0 N.A   N.A  
 4. Heart 398 2 1760.07 1.13632 1.85 (0.434,7.889)   1.288 (0.297,5.592)  
 5. Lung 73 0 233.99 0 N.A   N.A  
  1. NA not available