Table 3 Univariate and Multivariate cox regression for prostate cancer incidence only among organ-transplanted patients
Characteristics | N | Event | Duration | IR (per 1000) | Univariate | Multivariate | ||
|---|---|---|---|---|---|---|---|---|
HR | p value | HR | p value | |||||
Age (years), 20 ≤ Age < 50 | 6464 | 7 | 33,223.01 | 0.2107 | 0.088 (0.04,0.192) | < 0.001 | 0.111 (0.05,0.245) | < 0.001 |
50 ≤ Age < 65 | 6077 | 61 | 26,552.55 | 2.29733 | 1 (Ref.) | 1 (Ref.) | ||
65 ≤ Age ≤ 75 | 422 | 9 | 1537.49 | 5.85368 | 2.7 (1.339,5.444) | 2.809 (1.383,5.708) | ||
75 < Age | 7 | 0 | 18.31 | 0 | 0 (0) | 0 (0) | ||
Aspirin Yes | 973 | 7 | 4371.79 | 1.60118 | 1.318 (0.606,2.866) | 0.486 | 1.249 (0.568,2.749) | 0.5798 |
Statin Yes | 4312 | 15 | 19,924.96 | 0.75282 | 0.502 (0.286,0.883) | 0.017 | 1.088 (0.513,2.306) | 0.8257 |
Duration of Immunosuppressant (> 300 days) | 11,113 | 74 | 56,759.46 | 1.30375 | 1.508 (0.473,4.809) | 0.488 | 1.857 (0.581,5.937) | 0.2967 |
Hypertension Yes | 8135 | 40 | 38,322.42 | 1.04378 | 0.648 (0.414,1.013) | 0.057 | 1.213 (0.72,2.043) | 0.4685 |
Diabetes mellitus Yes | 6251 | 48 | 29,495.66 | 1.62736 | 1.79 (1.129,2.838) | 0.013 | 1.296 (0.814,2.063) | 0.2747 |
Dyslipidemia Yes | 4085 | 10 | 18,540.27 | 0.53937 | 0.346 (0.178,0.673) | 0.002 | 0.453 (0.19,1.079) | 0.0739 |
Transplanted organ | ||||||||
1. Kidney | 7026 | 21 | 33,615.34 | 0.62471 | 1 (Ref.) | 0.0001 | 1 (Ref.) | 0.3227 |
2. Liver | 5445 | 54 | 25,616.58 | 2.10801 | 3.398 (2.053,5.626) | 2.016 (1.067,3.809) | ||
3. Pancreas | 28 | 0 | 105.38 | 0 | N.A | N.A | ||
4. Heart | 398 | 2 | 1760.07 | 1.13632 | 1.85 (0.434,7.889) | 1.288 (0.297,5.592) | ||
5. Lung | 73 | 0 | 233.99 | 0 | N.A | N.A | ||