Skip to main content

Table 24 Studies in the Asia–Pacific region involving patients with GUTB

From: Serologic and urinary characteristics of laboratory-confirmed genitourinary tuberculosis at a tertiary hospital in the Philippines

Study (publication year) Size Setting (country) Population Outcomes Method
Mishra [33] (2020) 53 Department of Urology, Indira Gandhi Institute of Medical Sciences (India) Patients with confirmed GUTB Demographic, clinical presentation
Urinary profile, routine blood exams
Urine AFB smear test, urine MTB culture
Radiological examinations, cystoscopic examination, histopathological examinations
4-year prospective observational case series
Huang [10] (2019) 57 Chang Gung Memorial Hospital-Chiayi (Taiwan) Patients with diagnosis of GUTB with at least one of the following: positive MTB culture or histologic evidence Demographics, comorbidities, symptoms and signs
Results of mycobacterial smears and cultures, histopathology
CBCs, serum biochemistry profile
Chest radiography
GU tract operations, anti-TB therapy, complications, clinical outcomes
15-year retrospective study
Kim [35] (2018) 56 Severance Hospital, Seoul
(South Korea)
Participants older than 18 years diagnosed with GUTB based on presence of any clinical finding plus a positive result for one of the ff: (1) urine AFB, (2) urine MTB culture, (3) urine MTB PCR, or (4) histopathology Clinical and laboratory data
Diagnostic methods, treatment modalities and outcomes
11-year retrospective study
Cao [36] (2017) 419 Peking University First Hospital (China) All patients with clinical renal TB with microbiologic or histologic confirmation Demographics, clinical data, complications, treatment
Laboratory findings
Imaging findings
Pathologic features
15-year retrospective study
Krishnamoorthy [8] (2017) 110 Chennai, Tamil Nadu (India) Patients with either (1) proven GUTB based on urine AFB smear, AFB culture, histopathological evidence of TB, and/or by serological methods; or (2) presumed GUTB who had ≥ 2 consistent features on urological imaging or endoscopic evaluation Clinical history and examination
Serum biochemistry
Urine culture
Imaging findings
3-year retrospective study
Ye [37] (2016) 193 West China Hospital, Sichuan University (China) Cases with definite UTB based on results of comprehensive diagnosis, including clinical features, laboratory results (i.e., smear microscopy, MTB culture, real-time PCR, and histological patterns), radiological findings, and response to anti-TB therapy Demographic data, clinical history, prognosis
Radiological findings
Selected laboratory results
5-year cross-sectional study
Singh [38] (2013) 117 Urology Department of Institute of Post Graduate Medical Education and Research and SSKM Hospital (India) All cases clinically diagnosed as GUTB Clinical presentation
Urine AFB smear, urine MTB culture, urine PCR for MTB
Radiological and histopathological examinations
13-year retrospective study
Chandra [39] (2012) 25 Himalayan Institute of Medical Sciences, Uttarkhand State (India) Male patients with histopathologically confirmed GUTB Occupation, socioeconomic status
Clinical history
Relevant radiological, laboratory and histopathology findings
13-year retrospective study
Hsu [40] (2011) 64 National Taiwan University Hospital and Taipei Medical University – Wan Fang Hospital (Taiwan) All patients with urine culture-confirmed GUTB Clinical features
Laboratory characteristics
Treatment outcomes
Genotypic characteristics of MTB isolates
12-year retrospective study
Lee [17] (2011) 101 Department of Urology, Hanyang University College of Medicine (Korea) Patients diagnosed with GUTB based on the presence of one or more positivities in terms of histopathological findings, urine AFB smear, urine MTB culture, and urine PCR for MTB Yearly proportion, gender, patient distribution according to age, history of TB, and presence of other organ TB
Urinalysis findings
10-year retrospective study
Karnjanawanichkul [41] (2010) 35 Prince of Songkla University, Hat Yai, Songkhla (Thailand) Patients diagnosed with urinary tract TB by demonstration of AFB in urine smear, growth from urine MTB culture, or consistent histopathologic findings Demographic data, clinical features
Laboratory data
Chest x-ray, intravenous urography, ultrasonography, or endoscopic findings
10-year retrospective study
Takahashi [42] (2007) 12 Urology clinics of six medical centers, Hokkaido (Japan) Patients diagnosed with urinary TB based on NAAT or histopathology Demographic data, clinical features
Detection method for MTB
Diagnostic findings
Treatment, outcomes, and medication-related adverse events
5-year retrospective study
Hsieh [18] (2006) 31 Kaohsiunng Medical University Hospital, Kaohsiung (Taiwan) Patients diagnosed with GUTB based on microbiological or histological findings plus compatible clinical and roentgenographic findings Baseline characteristics, underlying diseases, treatment responses, and outcomes 11-year retrospective study
Buccholz [43] (2000) 55 Aga Khan University Hospital (Pakistan) In-patients with GUTB proven either by urine culture positivity for MTB, or histopathology Age, sex, concomitant diseases, medical history, symptoms, diagnosis, treatment and follow-up 13-year retrospective study
Ramanathan [34] (1998) 38 Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow (India) All patients with either: (1) urinary TB based on positive urine or pus cultures for MTB or histopathology, or (2) presumed urinary TB with ≥ 3 consistent features on urological imaging or endoscopy History and physical examination
Serum chemistry
Urine culture
Chest x-ray and ultrasonography
8-year retrospective study
Dy [16] (1995) 61 Santo Tomas University Hospital (Philippines) In-patients clinically diagnosed with GUTB Demographic features
Presenting manifestations, history of previous TB
Diagnostic modalities (radiographic, bacteriologic, histopathologic)
Therapeutic modalities
Case series
Tanchuco [15] (1987) 42 Philippine General Hospital and National Kidney Institute (Philippines) Patients with discharge diagnosis of urinary tract TB based on the presence of one of the following: positive urine AFB smear, positive urine AFB culture, or consistent histopathologic findings Clinical and laboratory parameters 6-year retrospective study
  1. GU genitourinary, MTB Mycobacterium tuberculosis, NAAT nucleic acid amplification test, PTB pulmonary tuberculosis, UTB urinary tuberculosis