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Table 3 Effects of crocin (6.25–100 mg/kg) on the seminiferous tubule area and germinal layer area

From: The protective effect of crocin on cisplatin-induced testicular impairment in rats

Groups

SA (µm2)  × 103

EA area (µm2) × 103

EA/SA * 100

Control

44.61 ± 8.10

35.32 ± 4.75

81.93 ± 8.89

CIS (7 mg/kg)

43.08 ± 2.94

25.89 ± 4.70***

59.08 ± 12.07**

CIS + CR6.25 mg/kg

42.53 ± 5.03

22.56 ± 4.18***

56.35 ± 8.19**

CIS + CR25 mg/kg

43.31 ± 5.12

23.96 ± 3.80***

59.48 ± 13.78**

CIS + CR100 mg/kg

44.83 ± 6.61

33.59 ± 6.40#

69.38 ± 10.98* #

  1. Values are expressed as mean ± standard deviation (n = 10). CIS: cisplatin; CR: crocin; CIS + CR 6.25–100: cisplatin (7 mg/kg) injected groups treated with 6.25–100 mg/kg crocin; SA: seminiferous tubule area; EA: germinal layer area. *p < 0.05, **p < 0.01 and ***p < 0.001 in comparison with the normal control group. #p < 0.05, ##p < 0.01 and ###p < 0.001 in comparison with the CIS group