|
Characteristics
|
OS
|
|---|
|
HR (95% CI)
|
p
|
|---|
|
Model 1a
| | |
|
T stage, Ta
|
1
|
< 0.001
|
|
T1
|
1.647 (0.501–5.411)
|
0.411
|
|
T2-4
|
4.78 (1.434–15.932)
|
0.011
|
|
N stage, N1-3 (vs. N0)
|
2.774 (1.185–6.492)
|
0.019
|
|
M stage, M1 (vs. M0)
|
3.435 (1.291–9.142)
|
0.013
|
|
FAM83H positive (vs. negative)
|
3.141 (1.587–6.215)
|
0.001
|
|
Model 2b
| | |
|
T stage, Ta
|
1
|
< 0.001
|
|
T1
|
1.831 (0.556–6.025)
|
0.32
|
|
T2-4
|
5.76 (1.707–19.436)
|
0.005
|
|
N stage, N1-3 (vs. N0)
|
2.382 (1.016–5.586)
|
0.046
|
|
M stage, M1 (vs. M0)
|
3.428 (1.277–9.196)
|
0.014
|
|
Combined expression, FAM83H−/Nectin1−
|
1
|
0.002
|
|
FAM83H−/Nectin1+ or FAM83H+/Nectin1−
|
4.731 (1.7–13.163)
|
0.003
|
|
FAM83H+/Nectin1+
|
5.46 (2.144–13.905)
|
< 0.001
|
- OS overall survival, HR hazard ratio, 95% CI 95% confidence interval
- aVariables considered in model 1 were histologic grade, T stage, N stage, M stage, TNM stage, FAM83H expression, and Nectin1 expression
- bVariables considered in model 2 were histologic grade, T stage, N stage, M stage, TNM stage, and combined expression of FAM83H and Nectin1
