Table 1 Baseline characteristics of the three studies used in the analysis
Variable | PLCO | SELECT | SABOR | SMD | |
|---|---|---|---|---|---|
n | 31,495 | 35,507 | 1790 | ||
Age (mean (SD)) | 62.47 (5.27) | 62.93 (6.80) | 58.68 (9.63) | 0.35 | |
African American = yes (%) | 1279 (4.1) | 5256 (14.8) | 173 (9.7) | 0.25 | |
BMI (mean (SD)) | 27.61 (4.19) | 28.59 (4.60) | 28.17 (4.80) | 0.15 | |
Family history of cancer = yes (%) | 2299 (7.4) | 5929 (16.7) | 424 (23.7) | 0.31 | |
Cancer diagnosis = yes (%) | 2798 (8.9) | 2550 (7.2) | 198 (11.1) | 0.09 | |
Cancer grade (%) | 0.28 | ||||
Low-grade cancer | 935 (33) | 1756 (69) | 169 (85) | ||
High-grade cancer (Gleason > 7) | 375 (13) | 146 (6) | 22 (11) | ||
Missing grade | 1488 (53) | 648 (25) | 7 (4) | ||
DRE = suspicious (%) | 2082 (6.6) | 3 (0.0) | 295 (16.5) | 0.44 | |
BPH = yes (%) | 6463 (20.6) | 5334 (15.0) | 626 (35.0) | 0.31 | |
Baseline PSA (mean (SD)) | 1.30 (0.88) | 1.35 (0.94) | 1.16 (0.79) | 0.15 | |
Follow-up years (median (IQR]) | 11.7 [9.6, 12.9] | 8.1 [6.1, 10.3] | 9.02 [4.76, 13.16] | 0.54 | |
PCa follow-up (median (IQR]) | 6.7 [3.5, 9.5] | 4.2[2.3, 6.0] | 5.62 [3.17, 8.32] | 0.49 | |
No PCa follow-up (median (IQR]) | 12.5 [10.5, 12.9] | 8.4[6.5, 10.4] | 9.74 [5.28, 13.44] | 0.60 | |