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Table 2 Cox proportional hazard models by study prior to AIC evaluation

From: Prediction of future risk of any and higher-grade prostate cancer based on the PLCO and SELECT trials

Study

Variable

Hazard ratio

CI 95%

P value

PLCO

Age

1.01

(1, 1.02)

0.08

Age and PSA interaction

0.89

(0.85, 0.94)

< 0.001*

BMI

1.01

(1, 1.02)

0.07

BPH

0.88

(0.81, 0.97)

0.01*

DRE

1.64

(1.46, 1.85)

< 0.001*

Family history of cancer

1.43

(1.27, 1.61)

< 0.001*

Finasteride use

0.69

(0.6, 0.79)

< 0.001*

Log (PSA)

5.52

(5.15, 5.93)

< 0.001*

African American

1.37

(1.15, 1.63)

< 0.001*

African American and BMI interaction

1.05

(0.89, 1.23)

0.58

SELECT

Age

1.01

(1, 1.02)

0.03*

Age and PSA interaction

0.83

(0.79, 0.88)

< 0.001*

BMI

1

(0.99, 1.01)

1

BPH

0.84

(0.75, 0.93)

0.001*

Family history of cancer

1.72

(1.58, 1.88)

< 0.001*

Finasteride use

0.98

(0.77, 1.25)

0.88

Log (PSA)

5.3

(4.92, 5.71)

< 0.001*

African American

1.29

(1.15, 1.44)

< 0.001*

African American and BMI interaction

1.15

(1.04, 1.27)

0.01*

  1. The bold and * denotes P-value < 0.05