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Fig. 2 | BMC Urology

Fig. 2

From: Metformin exerts an antitumor effect by inhibiting bladder cancer cell migration and growth, and promoting apoptosis through the PI3K/AKT/mTOR pathway

Fig. 2

The effects of metformin at different concentrations on the proliferation of T24 and 5637 cell lines. A The effects of different concentrations of metformin over time on the proliferative ability of T24 cell lines were observed using CCK-8 assays to measure proliferation. B The effects of different concentrations of metformin over time on the proliferative ability of 5637 cell lines were observed using CCK-8 assays to measure cell viability. C, D The effects of metformin at different concentrations on the proliferation of T24 and 5637 cell lines assessed using colony formation experiments. The cell clones were counted and the clone formation rate of each drug concentration treatment group was calculated using Quantity One software. The results are shown as the mean ± the standard deviation (SD) from three independent experiments and were compared with the values for the control (*P < 0.05, **P < 0.01). CCK-8, cell counting kit 8

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BMC Urology

ISSN: 1471-2490

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