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Table 5 Intervention trigger

From: Knowledge, attitudes, and practices of active surveillance in prostate cancer among urologists: a real-life survey from Brazil

Question

N

%

Intervention trigger

Which of the following options do you use to recommend conversion from active surveillance to definitive treatment?

*more than one answer was accepted

Patient’s preference

354

85.7

Change in rectal examination (worsening of clinical staging)

250

60.5

Single rising PSA level (PSA > 10 ng/mL)

133

32.0

Two or more consecutive rising in PSA levels (PSA > 10 ng/mL)

225

54.5

PSA doubling time < 3 years

110

26.4

Rising PSA density (> 15%)

78

18.9

Gleason score upgrading to 7 (3 + 4)

228

55.2

Gleason score upgrading to 7 (3 + 4) or greater on re-biopsy

303

73.4

Increased tumor volume on imaging (MRI)

167

40.4

Higher number of positive cores in re-biopsy (> 1/3)

276

66.8

Involvement > 50% in at least 1 core in re-biopsy

189

45.8

  1. MRI magnetic resonance imaging, PSA prostate-specific antigen