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Table 2 Kaplan–Meier estimator depending on baseline hemoglobin, LDH, GGT, ALP and CRP level within/outside the set reference range

From: Pre- and intratherapeutic predictors of overall survival in patients with advanced metastasized castration-resistant prostate cancer receiving Lu-177-PSMA-617 radioligand therapy

Baseline parameter

Reference range

Median survival within reference range

Median survival outside reference range

p value

Hemoglobin

 ≥ 10 g/dl

81.9 (n = 40)

44.0 (n = 12)

0.035

LDH

 ≤ 250 U/l

99.4 (n = 26)

42.0 (n = 26)

 < 0.001*

GGT

 ≤ 60 U/l

96.9 (n = 32)

42.0 (n = 20)

0.005

ALP

 ≤ 130 U/l

61.0 (n = 27)

42.0 (n = 25)

0.026

CRP

 ≤ 5 mg/l

116.1 (n = 23)

42.0 (n = 29)

 < 0.001*

  1. LDH, lactate dehydrogenase; GGT, gamma-glutamyl transferase; ALP, alkaline phosphatase; CRP, c-reactive protein; (*) statistically significant after adjusting for multiple testing