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Fig. 2 | BMC Urology

Fig. 2

From: A triple-classification for differentiating renal oncocytoma from renal cell carcinoma subtypes and CK7 expression evaluation: a radiomics analysis

Fig. 2

Workflow of radiomics methodology. (1) The example of tumor segmentation on the CT image of a cross-axial section. The contours were drawn slightly within the borders of the tumor. The tumor was segmented on both corticomedullary and nephrographic phase images, respectively. Thus, VOI was generated by a continuous layer of delineation. (2) Six types of radiomics features were analyzed via AK software. (3) LASSO was applied in the training set for feature selection. (4) The models were evaluated by ROC curve analysis. SHAP values were applied with the SVM models to transparentize the “black box.” (5) A nomogram that incorporates radiomics signature and clinical factors was constructed to provide a visual measure for customized evaluation, followed by decision curve analysis and calibration curve

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