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Table 1 Baseline characteristics of the study population

From: Neoadjuvant versus adjuvant chemotherapy in upper tract urothelial carcinoma: A nationwide cohort study

 

                                                                                    Before match

 

                                               After match

 
 

NUx

AC

NAC

p-value

 

AC

NAC

p-value

SMD

 

(n = 6627)

(n = 1984)

(n = 94)

(AC vs. NAC)

 

(n = 188)

(n = 94)

  

Age

67.9 ± 10.4

64.2 ± 9.3

65.2 ± 9.4

0.294

 

65.0 ± 8.9

65.2 ± 9.4

0.875

0.020

 

70.0 [61.0;76.0]

65.0 [58.0;71.0]

67.0 [60.0;72.0]

  

66.0 [59.5;72.0]

67.0 [60.0;72.0]

  

Age group

   

0.213

   

1.000

< 0.001

- <65

2236 (33.7%)

922 (46.5%)

37 (39.4%)

  

74 (39.4%)

37 (39.4%)

  

- ≥65

4391 (66.3%)

1062 (53.5%)

57 (60.6%)

  

114 (60.6%)

57 (60.6%)

  

Sex

   

0.333

   

1.000

< 0.001

- Male

4643 (70.1%)

1452 (73.2%)

64 (68.1%)

  

128 (68.1%)

64 (68.1%)

  

- Female

1984 (29.9%)

532 (26.8%)

30 (31.9%)

  

60 (31.9%)

30 (31.9%)

  

Diagnostic year

   

< 0.001

   

0.722

0.065

− 2004–2009

2062 (31.1%)

779 (39.3%)

19 (20.2%)

  

43 (22.9%)

19 (20.2%)

  

− 2010–2016

4565 (68.9%)

1205 (60.7%)

75 (79.8%)

  

145 (77.1%)

75 (79.8%)

  

CCI

   

0.010

   

1.000

< 0.001

- <4

4285 (64.7%)

1455 (73.3%)

57 (60.6%)

  

114 (60.6%)

57 (60.6%)

  

- ≥4

2342 (35.3%)

529 (26.7%)

37 (39.4%)

  

74 (39.4%)

37 (39.4%)

  
  1. Data are presented as n (%), mean ± standard deviation, or median [interquartile range]
  2. Abbreviations: NUx, Nephroureterectomy; AC, Adjuvant chemotherapy; NAC, Neoadjuvant chemotherapy; SMD, Standardized mean difference; CCI, Charlson Comorbidity Index