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Table 2 Impact of TNM stage, Gleason scores, and PSA levels on the survival of patients with advanced prostate cancer

From: Modified the 8th AJCC staging system for patients with advanced prostate cancer: a study based on SEER database

Variables

Univariable

Multivariable

HR (95%CI)

P

HR (95%CI)

P

T stage

    

T3a

Ref

   

T3b

2.00 (1.75–2.29)

< 0.001

1.33 (1.16–1.53)

< 0.001

T4

7.01 (6.26-8.00)

< 0.001

2.44 (2.11–2.82)

< 0.001

 N stage

    

N0

Ref

   

N1

3.60 (3.23–4.01)

< 0.001

1.09 (0.97–1.23)

0.153

M stage

    

M0

Ref

   

M1

17.49 (15.73–19.46)

< 0.001

5.08 (4.39–5.87)

< 0.001

Primary Gleason pattern scores

3.61 (3.33–3.91)

< 0.001

1.83 (1.68-2.00)

< 0.001

Secondary Gleason pattern scores

2.46 (2.28–2.65)

< 0.001

1.42 (1.32–1.54)

< 0.001

PSA levels

7.64 (6.76–8.64)

< 0.001

1.90 (1.62–2.22)

< 0.001

  1. Note: HR, hazard ratio; CI, confidence interval; PSA, prostate-specific antigen; Multivariable analysis adjusted for 5 other variables except the analysis variable
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BMC Urology

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